Beyond closing the deal

How quality culture can determine the success of pharma M&A

The smart way to health
  • Industry
  • 3 minute read
  • 19/03/26

Pharma M&A is reshaping global manufacturing networks — but true value isn’t created by assets alone. It’s created by people, behaviours and a shared commitment to quality. Our latest whitepaper explores why quality culture has become a decisive value driver in pharma integrations and outlines practical steps to build a patient-centric, sustainable culture that accelerates performance and protects deal value. Discover how to lead your quality culture by choice — not by chance.

Beyond closing the deal

How quality culture can determine the success of pharma M&A

Key insights 

  • Quality culture is a strategic value driver, directly influencing supply reliability, regulatory trust, talent retention and financial outcomes. 
  • Leading regulators now see quality culture as the foundation of reliable quality systems, enabling lower costs, fewer disruptions and greater long‑term value. 
  • 30% of M&A deals fail to meet financial targets due to cultural misalignment, highlighting why cultural signals should be assessed early in due diligence. 
  • A shared patient‑centric mindset transforms compliance into true ownership and accountability, aligning decisions across entities and enabling faster, more coherent integration. 
  • Strong cultural foundations protect reputation and deal value, while reducing the cost of poor quality, which can reach 10–40% of operational costs in pharma manufacturing. 
  • The paper presents a four-stage model for shaping quality culture: understanding the starting point, aligning leadership, co-creating future quality culture, and sustaining it through structured reinforcements. 
  • The paper includes  real-world integration examples from leadership workshops to gamified shopfloor learnings. 

Contact us
Philipp Hespe

Philipp Hespe

Partner, Swiss Quality and R&D Lead, PwC Switzerland

Luca Borrelli

Luca Borrelli

Partner, Swiss Health Industries Deals Leader, PwC Switzerland

Teena Madhvani

Teena Madhvani

Partner, People and Organisation, PwC Switzerland

Dr. Jens Neumann

Dr. Jens Neumann

Partner, Advisory, PwC Switzerland